BDBM202696 US10245267, Example 43::US10709712, Example 42::US9242969, 42::US9694016, 42

SMILES CC(=C)c1cc(nc(n1)N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=NZQDZMBWHLVRCS-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202696   

TargetRAF proto-oncogene serine/threonine-protein kinase [325-648](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM202696(US10245267, Example 43 | US10709712, Example 42 | ...)
Affinity DataIC50:  0.137nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent